Storage Spaces Direct has native support for persistent memory. Unlock unprecedented performance with native Storage Spaces Direct support for persistent memory modules, including Intel® Optane™ DC PM and NVDIMM-N. Use persistent memory as cache to accelerate the active working set, or as capacity to guarantee consistent low latency on the order of microseconds. Manage persistent memory just as you would any other drive in PowerShell or Windows Admin Center
Dell has published step-by-step guides for provisioning NVDIMMs within Windows Server 2019 for use with Hyper-V Guest OS's:
Step-by-step details are not available at this time. Microsoft will provide detailed documentation. See the resources listed below for information and a state of the ecosphere by Microsoft.